| Gene Information | |
|---|---|
| Gene Name | RQT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2202 |
| Protein Names | Activating signal cointegrator 1 complex subunit 3 (EC 3.6.4.12) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8N3C0 |
| Gene Card | ASCC3 |
| Uniprot ID | Q8N3C0 |
| Pfam | PF00270; PF00271; PF02889 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12077347}. |
| Pharmacological Animal Models | 0.021809(Chimpanzee);0.010025(Mouse);0.001466(Rat);0.019048(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6YXQ (X-ray 2.70A ) |
| DBSNP | rs9390698 rs6918004 rs7750940 rs57534235 rs9497983 rs17246013 rs17305382 rs35011147 rs3213542 rs240780 rs240768 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12077347, ECO:0000269|PubMed:29144457}. Nucleus speckle {ECO:0000269|PubMed:29144457, ECO:0000269|PubMed:29997253}. Cytoplasm, cytosol {ECO:0000269|PubMed:28757607}. Note=Colocalizes with ALKBH3 and ASCC2 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. {ECO:0000269|PubMed:29144457}. |
| Mouse PG classification | NA |
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