| Gene Information | |
|---|---|
| Gene Name | RPS6KB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 482 |
| Protein Names | Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta) |
| Target Name | ribosomal protein s6 kinase beta-2 |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000175634 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBS0 |
| Gene Card | RPS6KB2 |
| Uniprot ID | Q9UBS0 |
| Pfam | PF00069; PF00433 |
| In ASD | no |
| Allosteric Prediction | yes (0.602243714) |
| Ortholog in Animals | Alpaca_ RPS6KB2 ( ortholog_one2one ) Dog_ RPS6KB2 ( ortholog_one2one ) GuineaPig_ RPS6KB2 ( ortholog_one2one ) Macaque_ RPS6KB2 ( ortholog_one2one ) Mouse_ Rps6kb2 ( ortholog_one2one ) Pig_ RPS6KB2 ( ortholog_one2one ) Rat_ Rps6kb2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RPS6KA1, RPS6KA5, RPS6KB1, RPS6KA3, RPS6KA2, RPS6KA4, RPS6KA6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs55987642 rs55642995 rs13859 rs374535834 |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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