| Gene Information | |
|---|---|
| Gene Name | TRPC5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 973 |
| Protein Names | Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5) |
| Target Name | short transient receptor potential channel 5 |
| Target Type | Clinical trial target |
| Gene Age | 950 ( ENSG00000072315 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9UL62 |
| Gene Card | TRPC5 |
| Uniprot ID | Q9UL62 |
| Pfam | PF12796; PF00520; PF08344 |
| In ASD | no |
| Allosteric Prediction | no (-0.133840387) |
| Ortholog in Animals | Alpaca_ TRPC5 ( ortholog_one2one ) Dog_ TRPC5 ( ortholog_one2one ) GuineaPig_ TRPC5 ( ortholog_one2one ) Macaque_ TRPC5 ( ortholog_one2one ) Mouse_ Trpc5 ( ortholog_one2one ) Pig_ TRPC5 ( ortholog_one2one ) Rat_ Trpc5 ( ortholog_one2one ) Rabbit_ TRPC5 ( ortholog_one2one ) |
| Ohnologs | TRPC4, TRPC1 |
| Paralogs | TRPC4, TRPC1, TRPC7, TRPC3, TRPC6 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole. {ECO:0000269|PubMed:9687496}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6YSN (EM 3.00A ) 7D4P (EM 2.70A ) 7D4Q (EM 2.74A ) 7E4T (EM 3.00A ) 7WDB (EM 2.40A ) |
| DBSNP | rs36047478 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16284075}; Multi-pass membrane protein {ECO:0000269|PubMed:16284075}. |
| Mouse PG classification | NA |
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