| Gene Information | |
|---|---|
| Gene Name | PON2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 354 |
| Protein Names | Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105854 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q15165 |
| Gene Card | PON2 |
| Uniprot ID | Q15165 |
| Pfam | PF01731 |
| In ASD | no |
| Allosteric Prediction | no (-0.269817033) |
| Ortholog in Animals | Alpaca_ PON2 ( ortholog_one2one ) Dog_ PON2 ( ortholog_one2one ) GuineaPig_ PON2 ( ortholog_one2one ) Macaque_ PON2 ( ortholog_one2one ) Mouse_ Pon2 ( ortholog_one2one ) Pig_ PON2 ( ortholog_one2one ) Rat_ Pon2 ( ortholog_one2one ) Rabbit_ PON2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PON1, PON3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest expression in liver, lung, placenta, testis and heart. {ECO:0000269|PubMed:11579088}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12026 rs17876152 rs7493 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:11579088}; Peripheral membrane protein {ECO:0000269|PubMed:11579088}. |
| Mouse PG classification | NA |
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