| Gene Information | |
|---|---|
| Gene Name | RPN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 607 |
| Protein Names | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000163902 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P04843 |
| Gene Card | RPN1 |
| Uniprot ID | P04843 |
| Pfam | PF04597 |
| In ASD | no |
| Allosteric Prediction | yes (0.070986532) |
| Ortholog in Animals | Alpaca_ RPN1 ( ortholog_one2one ) Dog_ RPN1 ( ortholog_one2one ) GuineaPig_ RPN1 ( ortholog_one2one ) Macaque_ RPN1 ( ortholog_one2one ) Mouse_ Rpn1 ( ortholog_one2one ) Pig_ RPN1 ( ortholog_one2one ) Rat_ Rpn1 ( ortholog_one2one ) Rabbit_ RPN1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested. {ECO:0000269|PubMed:12887896}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002223(Rat);0.041026(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6S7O (EM 3.50A ) 6S7T (EM 3.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250|UniProtKB:E2RQ08, ECO:0000250|UniProtKB:Q9GMB0}. Endoplasmic reticulum membrane; Single-pass type I membrane protein {ECO:0000305}. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Mouse PG classification | NA |
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