| Gene Information | |
|---|---|
| Gene Name | RPL6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | 60S ribosomal protein L6 (Large ribosomal subunit protein eL6) (Neoplasm-related protein C140) (Tax-responsive enhancer element-binding protein 107) (TaxREB107) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000089009 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q02878 |
| Gene Card | RPL6 |
| Uniprot ID | Q02878 |
| Pfam | PF01159; PF03868 |
| In ASD | no |
| Allosteric Prediction | no (-0.588143106) |
| Ortholog in Animals | Alpaca_ RPL6 ( ortholog_one2one ) GuineaPig_ RPL6 ( ortholog_one2one ) Mouse_ Rpl6 ( ortholog_one2one ) Pig_ RPL6 ( ortholog_one2one ) Rat_ AC120310.1 ( ortholog_one2many ) Rat_ Rpl6 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001042(Rat);0.211317(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 4UG0 (EM - ) 4V6X (EM 5.00A ) 5AJ0 (EM 3.50A ) 5LKS (EM 3.60A ) 5T2C (EM 3.60A ) 6IP5 (EM 3.90A ) 6IP6 (EM 4.50A ) 6IP8 (EM 3.90A ) 6LQM (EM 3.09A ) 6LSR (EM 3.13A ) 6LSS (EM 3.23A ) 6LU8 (EM 3.13A ) 6OLE (EM 3.10A ) 6OLF (EM 3.90A ) 6OLG (EM 3.40A ) 6OLI (EM 3.50A ) 6OLZ (EM 3.90A ) 6OM0 (EM 3.10A ) 6OM7 (EM 3.70A ) 6QZP (EM 2.90A ) 6W6L (EM 3.84A ) 6XA1 (EM 2.80A ) 6Y0G (EM 3.20A ) 6Y2L (EM 3.00A ) 6Y57 (EM 3.50A ) 6Y6X (EM 2.80A ) 6Z6L (EM 3.00A ) 6Z6M (EM 3.10A ) 6Z6N (EM 2.90A ) 6ZM7 (EM 2.70A ) 6ZME (EM 3.00A ) 6ZMI (EM 2.60A ) 6ZMO (EM 3.10A ) 7BHP (EM 3.30A ) 7F5S (EM 2.72A ) |
| DBSNP | rs17851813 rs16942044 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:25957688}. Cytoplasm {ECO:0000305|PubMed:23636399, ECO:0000305|PubMed:25901680}. Rough endoplasmic reticulum {ECO:0000250|UniProtKB:Q2YGT9}. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). {ECO:0000250|UniProtKB:Q2YGT9, ECO:0000269|PubMed:25957688}. |
| Mouse PG classification | NA |
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