| Gene Information | |
|---|---|
| Gene Name | PPP4R1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 950 |
| Protein Names | Serine/threonine-protein phosphatase 4 regulatory subunit 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154845 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TF05 |
| Gene Card | PPP4R1 |
| Uniprot ID | Q8TF05 |
| Pfam | PF02985; PF15017 |
| In ASD | no |
| Allosteric Prediction | yes (0.05424405) |
| Ortholog in Animals | Alpaca_ PPP4R1 ( ortholog_one2one ) Dog_ PPP4R1 ( ortholog_one2one ) GuineaPig_ PPP4R1 ( ortholog_one2one ) Macaque_ PPP4R1 ( ortholog_one2one ) Mouse_ Ppp4r1 ( ortholog_one2one ) Pig_ PPP4R1 ( ortholog_one2one ) Rat_ Ppp4r1 ( ortholog_one2one ) Rabbit_ PPP4R1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP2R1A, PPP2R1B |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high expression in cultured mesangial cells. Isoform 1 and isoform 2 are expressed in renal tissues. {ECO:0000269|PubMed:11729228}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1056191 rs329003 rs2306134 rs2306134 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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