| Gene Information | |
|---|---|
| Gene Name | RP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2156 |
| Protein Names | Oxygen-regulated protein 1 (Retinitis pigmentosa 1 protein) (Retinitis pigmentosa RP1 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104237 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P56715 |
| Gene Card | RP1 |
| Uniprot ID | P56715 |
| Pfam | PF03607 |
| In ASD | no |
| Allosteric Prediction | no (-0.741031486) |
| Ortholog in Animals | Alpaca_ RP1 ( ortholog_one2one ) Dog_ RP1 ( ortholog_one2one ) Macaque_ RP1 ( ortholog_one2one ) Mouse_ Rp1 ( ortholog_one2one ) Pig_ RP1 ( ortholog_one2one ) Rat_ Rp1 ( ortholog_one2one ) Rabbit_ RP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RP1L1 |
| Tissue | NA |
| Tissue Specificity | Expressed in retina. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, spleen and pancreas. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.086957(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1422215201 rs180729424 rs145691085 rs16920614 rs77775126 rs1166678265 rs372551375 rs201725231 rs199879316 rs28399531 rs444772 rs16920621 rs200135800 rs2293869 rs756775228 rs186594858 rs139294220 rs1338252422 rs35084330 rs760740229 rs446227 rs414352 rs143088423 rs371969576 rs140137224 rs61739567 rs149282954 rs137887415 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:11773008}. Note=Specifically localized in the connecting cilia of rod and cone photoreceptors. |
| Mouse PG classification | HPG |
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