| Gene Information | |
|---|---|
| Gene Name | RP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Microtubule-associated protein RP/EB family member 2 (APC-binding protein EB2) (End-binding protein 2) (EB2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104237 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q15555 |
| Gene Card | MAPRE2 |
| Uniprot ID | Q15555 |
| Pfam | PF00307; PF03271 |
| In ASD | no |
| Allosteric Prediction | no (-0.741031486) |
| Ortholog in Animals | Alpaca_ RP1 ( ortholog_one2one ) Dog_ RP1 ( ortholog_one2one ) Macaque_ RP1 ( ortholog_one2one ) Mouse_ Rp1 ( ortholog_one2one ) Pig_ RP1 ( ortholog_one2one ) Rat_ Rp1 ( ortholog_one2one ) Rabbit_ RP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RP1L1 |
| Tissue | NA |
| Tissue Specificity | Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes. {ECO:0000269|PubMed:9233623}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.017647(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs864309719 rs864309717 rs864309720 rs11538993 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10188731}. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules. |
| Mouse PG classification | HPG |
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