| Gene Information | |
|---|---|
| Gene Name | RORB |
| Organism | Homo sapiens (Human) |
| Gene Length | 470 |
| Protein Names | Nuclear receptor ROR-beta (Nuclear receptor RZR-beta) (Nuclear receptor subfamily 1 group F member 2) (Retinoid-related orphan receptor-beta) |
| Target Name | nuclear receptor ror-beta |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000198963 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92753 |
| Gene Card | RORB |
| Uniprot ID | Q92753 |
| Pfam | PF00104; PF00105 |
| In ASD | no |
| Allosteric Prediction | no (-0.08408365) |
| Ortholog in Animals | Alpaca_ RORB ( ortholog_one2one ) Dog_ RORB ( ortholog_one2one ) GuineaPig_ RORB ( ortholog_one2one ) Macaque_ RORB ( ortholog_one2one ) Mouse_ Rorb ( ortholog_one2one ) Pig_ RORB ( ortholog_one2one ) Rat_ Rorb ( ortholog_one2one ) Rabbit_ RORB ( ortholog_one2one ) |
| Ohnologs | RORA, RORC |
| Paralogs | NR1H4, VDR, RARG, NR1D2, RARA, PPARD, NR1H2, RORC, THRB, NR1D1, NR1H3, NR1I2, PPARG, NR1I3, RARB, PPARA, RORA, THRA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs869312971 rs869312972 |
| Subcellular location [CC] | Nucleus, nucleoplasm {ECO:0000269|PubMed:27352968}. |
| Mouse PG classification | NA |
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