| Gene Information | |
|---|---|
| Gene Name | ROMK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 391 |
| Protein Names | ATP-sensitive inward rectifier potassium channel 1 (ATP-regulated potassium channel ROM-K) (Inward rectifier K(+) channel Kir1.1) (Potassium channel, inwardly rectifying subfamily J member 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P48048 |
| Gene Card | KCNJ1 |
| Uniprot ID | P48048 |
| Pfam | PF01007; PF17655 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | In the kidney and pancreatic islets. Lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver. {ECO:0000269|PubMed:7635463}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34191956 rs1213764655 rs104894250 rs373745258 rs766131330 rs104894251 rs104894254 rs104894253 rs104894246 rs104894245 rs753949204 rs59172778 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12684516}; Multi-pass membrane protein {ECO:0000269|PubMed:12684516}. Note=Phosphorylation at Ser-44 by SGK1 is necessary for its expression at the cell membrane. {ECO:0000269|PubMed:12684516}. |
| Mouse PG classification | NA |
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