| Gene Information | |
|---|---|
| Gene Name | ROGDI |
| Organism | Homo sapiens (Human) |
| Gene Length | 287 |
| Protein Names | Protein rogdi homolog |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000067836 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9GZN7 |
| Gene Card | ROGDI |
| Uniprot ID | Q9GZN7 |
| Pfam | PF10259 |
| In ASD | no |
| Allosteric Prediction | no (-1.282292591) |
| Ortholog in Animals | Alpaca_ ROGDI ( ortholog_one2one ) Dog_ ROGDI ( ortholog_one2one ) GuineaPig_ ROGDI ( ortholog_one2one ) Macaque_ ROGDI ( ortholog_one2one ) Mouse_ Rogdi ( ortholog_one2one ) Rat_ Rogdi ( ortholog_one2one ) Rabbit_ ROGDI ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in spinal cord, brain, heart and bone marrow. Also expressed in fetal brain and liver. {ECO:0000269|PubMed:22482807}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XQH (X-ray 2.04A ) 5XQI (X-ray 2.80A ) |
| DBSNP | rs2305659 |
| Subcellular location [CC] | Nucleus envelope {ECO:0000269|PubMed:22482807}. Presynapse {ECO:0000250|UniProtKB:Q4V7D2}. Cell projection, axon {ECO:0000250|UniProtKB:Q4V7D2}. Perikaryon {ECO:0000250|UniProtKB:Q4V7D2}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q4V7D2}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q4V7D2}. Note=Detected primarily at presynaptic sites on axons, and to a lesser degree in soma and dendrites. Not detected at post-synaptic sites. {ECO:0000250|UniProtKB:Q4V7D2}. |
| Mouse PG classification | NA |
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