| Gene Information | |
|---|---|
| Gene Name | CKLF |
| Organism | Homo sapiens (Human) |
| Gene Length | 152 |
| Protein Names | Chemokine-like factor (C32) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000217555 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UBR5 |
| Gene Card | CKLF |
| Uniprot ID | Q9UBR5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.199009589) |
| Ortholog in Animals | Dog_ CKLF ( ortholog_one2one ) GuineaPig_ CKLF ( ortholog_one2one ) Mouse_ Cklf ( ortholog_one2one ) Pig_ CKLF ( ortholog_one2one ) Rat_ Cklf ( ortholog_one2one ) Rabbit_ CKLF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CMTM2, PLP2, MAL, CMTM3, PLLP, CMTM4, CMTM8, CMTM1, MAL2, CMTM7, MALL, CMTM6, MARVELD1, CMTM5 |
| Tissue | NA |
| Tissue Specificity | Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skeletal muscle, liver, thymus colon, prostate and fetal spleen and liver. {ECO:0000269|PubMed:11415443}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Secreted {ECO:0000269|PubMed:11415443, ECO:0000269|PubMed:16137713}.; [Isoform 2]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.; [Isoform 4]: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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