| Gene Information | |
|---|---|
| Gene Name | RNH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 286 |
| Protein Names | Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000023191 ) 3 ( ENSG00000276230 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60930 |
| Gene Card | RNASEH1 |
| Uniprot ID | O60930 |
| Pfam | PF01693; PF00075 |
| In ASD | no |
| Allosteric Prediction | no (-0.171586161) |
| Ortholog in Animals | Alpaca_ RNH1 ( ortholog_one2one ) Dog_ RNH1 ( ortholog_one2one ) GuineaPig_ RNH1 ( ortholog_one2one ) Mouse_ Rnh1 ( ortholog_one2one ) Pig_ RNH1 ( ortholog_one2one ) Rat_ Rnh1 ( ortholog_one2one ) |
| Ohnologs | NLRP2, NLRP4, NLRP13, NLRP11 |
| Paralogs | CARMIL3, CARMIL1, PPP1R37, CARMIL2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2QK9 (X-ray 2.55A ) 2QKB (X-ray 2.40A ) 2QKK (X-ray 3.20A ) 3BSU (X-ray 2.10A ) 6VRD (X-ray 1.30A ) |
| DBSNP | rs1136545 rs766294940 rs1057517675 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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