| Gene Information | |
|---|---|
| Gene Name | RIN2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 895 |
| Protein Names | Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000132669 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8WYP3 |
| Gene Card | RIN2 |
| Uniprot ID | Q8WYP3 |
| Pfam | PF00788; PF02204 |
| In ASD | no |
| Allosteric Prediction | no (-0.915542092) |
| Ortholog in Animals | Alpaca_ RIN2 ( ortholog_one2one ) Dog_ RIN2 ( ortholog_one2one ) GuineaPig_ RIN2 ( ortholog_one2one ) Macaque_ RIN2 ( ortholog_one2one ) Mouse_ Rin2 ( ortholog_one2one ) Rat_ Rin2 ( ortholog_one2one ) Rabbit_ RIN2 ( ortholog_one2one ) |
| Ohnologs | RIN3, RIN1 |
| Paralogs | RINL, RIN3, RIN1, VPS9D1, RABGEF1, GAPVD1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, kidney, lung placenta. Expressed at low level in skeletal muscle, spleen and peripheral blood. {ECO:0000269|PubMed:11733506}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3803981 rs199603 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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