| Gene Information | |
|---|---|
| Gene Name | RNF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 113 |
| Protein Names | RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000114125 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBF6 |
| Gene Card | RNF7 |
| Uniprot ID | Q9UBF6 |
| Pfam | PF12678 |
| In ASD | no |
| Allosteric Prediction | no (-0.669897706) |
| Ortholog in Animals | Alpaca_ RNF7 ( ortholog_one2one ) Dog_ RNF7 ( ortholog_one2one ) GuineaPig_ RNF7 ( ortholog_one2one ) Macaque_ RNF7 ( ortholog_one2one ) Mouse_ Rnf7l ( ortholog_one2many ) Mouse_ Rnf7 ( ortholog_one2many ) Pig_ RNF7 ( ortholog_one2one ) Rat_ Rnf7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RBX1, ANAPC11 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, liver, skeletal muscle and pancreas. At very low levels expressed in brain, placenta and lung. {ECO:0000269|PubMed:10512750}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ECL (NMR - ) 7ONI (EM 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10082581}. Nucleus {ECO:0000269|PubMed:10082581}. |
| Mouse PG classification | NA |
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