Gene Information
Gene NameRNF5
OrganismHomo sapiens (Human)
Gene Length180
Protein NamesE3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1)
Target NameNA
Target TypeNA
Gene Age3 ( ENSG00000183574 )
544 ( ENSG00000204308 )
3 ( ENSG00000223767 )
3 ( ENSG00000225452 )
3 ( ENSG00000227277 )
3 ( ENSG00000228405 )
3 ( ENSG00000228907 )
Evolutionary StageEukaryota
AlphaFoldDBQ99942
Gene CardRNF5
Uniprot IDQ99942
PfamNA
In ASDno
Allosteric Predictionno (-0.455681389)
Ortholog in AnimalsAlpaca_ RNF5 ( ortholog_one2many )
Dog_ RNF5 ( ortholog_one2one )
GuineaPig_ RNF5 ( ortholog_one2one )
Macaque_ RNF5 ( ortholog_one2one )
Mouse_ Rnf5 ( ortholog_one2one )
Pig_ RNF5 ( ortholog_one2one )
Rat_ Rnf5 ( ortholog_one2one )
Rabbit_ RNF5 ( ortholog_one2one )
OhnologsRNF185
ParalogsRNF185
TissueNA
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:9533025}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:9533025};
Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:19285439};
Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:19285439};
Multi-pass membrane protein {ECO:0000255}. Note=Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles. {ECO:0000269|PubMed:9533025}.
Mouse PG classificationNA
click here to return to the previous page