| Gene Information | |
|---|---|
| Gene Name | UBE2B |
| Organism | Homo sapiens (Human) |
| Gene Length | 152 |
| Protein Names | Ubiquitin-conjugating enzyme E2 B (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme B) (RAD6 homolog B) (HR6B) (hHR6B) (Ubiquitin carrier protein B) (Ubiquitin-conjugating enzyme E2-17 kDa) (Ubiquitin-protein ligase B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000119048 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P63146 |
| Gene Card | UBE2B |
| Uniprot ID | P63146 |
| Pfam | PF00179 |
| In ASD | no |
| Allosteric Prediction | no (-0.327663086) |
| Ortholog in Animals | Alpaca_ UBE2B ( ortholog_one2one ) Dog_ UBE2B ( ortholog_one2one ) GuineaPig_ UBE2B ( ortholog_one2one ) Macaque_ UBE2B ( ortholog_one2one ) Mouse_ Ube2b ( ortholog_one2one ) Pig_ UBE2B ( ortholog_one2one ) Rat_ Ube2b ( ortholog_one2one ) Rabbit_ UBE2B ( ortholog_one2one ) |
| Ohnologs | UBE2A |
| Paralogs | UBE2T, UBE2O, UBE2J2, UBE2A, UBE2C, UBE2H, UBE2V1, UBE2K, UBE2W, UBE2Z, UBE2F, UBE2G2, UBE2I, UBE2V2, UBE2N, UBE2NL, PEDS1, UBE2U, UBE2J1, UBE2G1, UBE2S, CDC34, UBE2R2, AKTIP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JAS (NMR - ) 2Y4W (NMR - ) 2YB6 (X-ray 1.50A ) 2YBF (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P63149}. Nucleus {ECO:0000250|UniProtKB:P63149}. Note=In peripheral neurons, expressed both at the plasma membrane and in nuclei. {ECO:0000250|UniProtKB:P63149}. |
| Mouse PG classification | NA |
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