| Gene Information | |
|---|---|
| Gene Name | RNF21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 488 |
| Protein Names | E3 ubiquitin-protein ligase TRIM34 (EC 2.3.2.27) (Interferon-responsive finger protein 1) (RING finger protein 21) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BYJ4 |
| Gene Card | TRIM34 |
| Uniprot ID | Q9BYJ4 |
| Pfam | PF00622; PF00643 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | [Isoform 1]: Is the most abundant form. It is highly expressed in the placenta, spleen, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:11013086}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2EGP (NMR - ) |
| DBSNP | rs6578670 rs3740997 rs16933844 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17156811, ECO:0000269|PubMed:31487507, ECO:0000269|PubMed:32282853}. Mitochondrion {ECO:0000269|PubMed:31956709}. Note=Localizes in cytoplasmic bodies together with TRIM5 and incoming HIV-1 capsids during infection. {ECO:0000269|PubMed:32282853}. |
| Mouse PG classification | NA |
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