Gene Information
Gene NameRNF200
OrganismHomo sapiens (Human)
Gene Length731
Protein NamesE3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ8NHY2
Gene CardCOP1
Uniprot IDQ8NHY2
PfamPF00400
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed at low level. Expressed at higher level in testis, placenta, skeletal muscle and heart. {ECO:0000269|PubMed:12615916, ECO:0000269|PubMed:15103385}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.047368(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5HQG  (X-ray  2.00A  5IGQ  (X-ray  3.90A 
DBSNP NA 
Subcellular location [CC]Nucleus speckle. Cytoplasm. Note=In the nucleus, it forms nuclear speckles.
Mouse PG classificationNA
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