Gene Information
Gene NameRNF196
OrganismHomo sapiens (Human)
Gene Length664
Protein NamesE3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING finger protein 196) (RING-type E3 ubiquitin transferase CHFR)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96EP1
Gene CardCHFR
Uniprot IDQ96EP1
PfamPF00498; PF10283; PF17979
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:10935642}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1LGP  (X-ray  2.00A  1LGQ  (X-ray  2.10A  2XOC  (X-ray  1.89A  2XOY  (X-ray  2.60A  2XOZ  (X-ray  2.37A  2XP0  (X-ray  1.98A 
DBSNP rs1176037831  rs115096950  rs2306541  rs2306536 
Subcellular location [CC]Nucleus, PML body {ECO:0000269|PubMed:11912157, ECO:0000269|PubMed:15467728, ECO:0000269|PubMed:18172500}.
Mouse PG classificationNA
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