| Gene Information | |
|---|---|
| Gene Name | RNF181 |
| Organism | Homo sapiens (Human) |
| Gene Length | 153 |
| Protein Names | E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000168894 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P0P0 |
| Gene Card | RNF181 |
| Uniprot ID | Q9P0P0 |
| Pfam | PF13639 |
| In ASD | no |
| Allosteric Prediction | no (-0.513986366) |
| Ortholog in Animals | Alpaca_ RNF181 ( ortholog_one2one ) Dog_ RNF181 ( ortholog_one2one ) GuineaPig_ RNF181 ( ortholog_one2one ) Macaque_ RNF181 ( ortholog_one2one ) Pig_ RNF181 ( ortholog_one2one ) Rat_ Rnf181 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RNF126, RNF115 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest levels in liver and heart and lowest levels in brain and skeletal muscle. Expressed in platelets (at protein level). {ECO:0000269|PubMed:18331836}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6643 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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