| Gene Information | |
|---|---|
| Gene Name | RNF158 |
| Organism | Homo sapiens (Human) |
| Gene Length | 729 |
| Protein Names | E3 ubiquitin-protein ligase SH3RF2 (EC 2.3.2.27) (Heart protein phosphatase 1-binding protein) (HEPP1) (POSH-eliminating RING protein) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (RING-type E3 ubiquitin transferase SH3RF2) (SH3 domain-containing RING finger protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TEC5 |
| Gene Card | SH3RF2 |
| Uniprot ID | Q8TEC5 |
| Pfam | PF00018; PF07653; PF14604; PF13445 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Heart (at protein level). Up-regulated in colon cancer tissues as compared to normal colon tissues (at protein level). Testis. In the heart, present in the apex, left atrium, right atrium, left ventricle and right ventricle, but not in the aorta. {ECO:0000269|PubMed:19945436, ECO:0000269|PubMed:24130170}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34739859 rs34942619 rs758037 rs35165046 rs2962525 rs11435 rs1056149 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:24130170}. |
| Mouse PG classification | NA |
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