| Gene Information | |
|---|---|
| Gene Name | NCBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 790 |
| Protein Names | Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000136937 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q09161 |
| Gene Card | NCBP1 |
| Uniprot ID | Q09161 |
| Pfam | PF02854; PF09088; PF09090 |
| In ASD | no |
| Allosteric Prediction | no (-0.351295347) |
| Ortholog in Animals | Alpaca_ NCBP1 ( ortholog_one2one ) Dog_ NCBP1 ( ortholog_one2one ) GuineaPig_ NCBP1 ( ortholog_one2one ) Macaque_ NCBP1 ( ortholog_one2one ) Mouse_ Ncbp1 ( ortholog_one2one ) Pig_ NCBP1 ( ortholog_one2one ) Rat_ Ncbp1 ( ortholog_one2one ) Rabbit_ NCBP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.329563(Mouse);NULL(Rat);0.196819(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1H2T (X-ray 2.15A ) 1H2U (X-ray 2.40A ) 1H2V (X-ray 2.00A ) 1H6K (X-ray 2.00A ) 1N52 (X-ray 2.11A ) 1N54 (X-ray 2.72A ) 3FEX (X-ray 3.55A ) 3FEY (X-ray 2.20A ) 5OO6 (X-ray 2.80A ) 5OOB (X-ray 2.79A ) 6D0Y (X-ray 2.68A ) 7ABG (EM 7.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19648179}. Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000269|PubMed:17289661}. |
| Mouse PG classification | NA |
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