| Gene Information | |
|---|---|
| Gene Name | RND3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3) |
| Target Name | rho-related gtp-binding protein rhoe |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000115963 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P61587 |
| Gene Card | RND3 |
| Uniprot ID | P61587 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.41191586) |
| Ortholog in Animals | Alpaca_ RND3 ( ortholog_one2one ) Dog_ RND3 ( ortholog_one2one ) GuineaPig_ RND3 ( ortholog_one2one ) Macaque_ RND3 ( ortholog_one2one ) Mouse_ Rnd3 ( ortholog_one2one ) Pig_ RND3 ( ortholog_one2one ) Rat_ Rnd3 ( ortholog_one2one ) Rabbit_ RND3 ( ortholog_one2one ) |
| Ohnologs | RND2, RND1 |
| Paralogs | RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOJ, RHOA, RHOC, RHOB, RHOV, RHOQ, RHOBTB2, RND2, RHOD, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1M7B (X-ray 2.00A ) 2V55 (X-ray 3.70A ) 4BG6 (X-ray 2.30A ) 7OBC (X-ray 1.90A ) 7OBD (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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