| Gene Information | |
|---|---|
| Gene Name | RNASEH2A |
| Organism | Homo sapiens (Human) |
| Gene Length | 299 |
| Protein Names | Ribonuclease H2 subunit A (RNase H2 subunit A) (EC 3.1.26.4) (Aicardi-Goutieres syndrome 4 protein) (AGS4) (RNase H(35)) (Ribonuclease HI large subunit) (RNase HI large subunit) (Ribonuclease HI subunit A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000104889 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | O75792 |
| Gene Card | RNASEH2A |
| Uniprot ID | O75792 |
| Pfam | PF01351 |
| In ASD | no |
| Allosteric Prediction | no (-0.626936731) |
| Ortholog in Animals | Alpaca_ RNASEH2A ( ortholog_one2one ) Dog_ RNASEH2A ( ortholog_one2one ) GuineaPig_ RNASEH2A ( ortholog_one2one ) Macaque_ RNASEH2A ( ortholog_one2one ) Mouse_ Rnaseh2a ( ortholog_one2one ) Pig_ RNASEH2A ( ortholog_one2one ) Rat_ Rnaseh2a ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005157(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3P56 (X-ray 4.06A ) 3PUF (X-ray 3.10A ) |
| DBSNP | rs76857106 rs76436818 rs77103971 rs7247284 rs62619782 rs79767407 rs75718910 rs79843600 rs15389 rs770898096 rs75037667 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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