| Gene Information | |
|---|---|
| Gene Name | RNASE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 156 |
| Protein Names | Ribonuclease pancreatic (EC 4.6.1.18) (HP-RNase) (RIB-1) (RNase UpI-1) (Ribonuclease 1) (RNase 1) (Ribonuclease A) (RNase A) |
| Target Name | ribonuclease pancreatic |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000129538 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P07998 |
| Gene Card | RNASE1 |
| Uniprot ID | P07998 |
| Pfam | PF00074 |
| In ASD | no |
| Allosteric Prediction | no (-0.464783064) |
| Ortholog in Animals | Alpaca_ RNASE1 ( ortholog_one2one ) Dog_ RAC1 ( ortholog_one2one ) Macaque_ RNASE1 ( ortholog_one2one ) Mouse_ Rnase1 ( ortholog_one2one ) Pig_ RNASE1 ( ortholog_one2one ) Rat_ Rnase1l1 ( ortholog_one2many ) Rat_ Rnase1 ( ortholog_one2many ) Rat_ Rnase1l2 ( ortholog_one2many ) Rabbit_ RNASE1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RNASE10, RNASE9, RNASE6, RNASE2, RNASE3, RNASE11, ANG, RNASE4, RNASE12, RNASE13, RNASE8, RNASE7 |
| Tissue | NA |
| Tissue Specificity | Pancreas and other tissues and body fluids (indicating it may have other physiological functions besides its role in digestion). |
| Pharmacological Animal Models | 0.140380(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1DZA (X-ray 1.65A ) 1E21 (X-ray 1.90A ) 1H8X (X-ray 2.00A ) 1Z7X (X-ray 1.95A ) 2E0J (X-ray 1.60A ) 2E0L (X-ray 1.60A ) 2E0M (X-ray 1.70A ) 2E0O (X-ray 2.00A ) 2K11 (NMR - ) 2Q4G (X-ray 1.95A ) 3F8G (X-ray 2.60A ) 4KXH (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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