| Gene Information | |
|---|---|
| Gene Name | RIZ |
| Organism | Homo sapiens (Human) |
| Gene Length | 1718 |
| Protein Names | PR domain zinc finger protein 2 (EC 2.1.1.355) (GATA-3-binding protein G3B) (Lysine N-methyltransferase 8) (MTB-ZF) (MTE-binding protein) (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc finger protein) (Zinc finger protein RIZ) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13029 |
| Gene Card | PRDM2 |
| Uniprot ID | Q13029 |
| Pfam | PF00856; PF00096 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. {ECO:0000269|PubMed:8654390, ECO:0000269|PubMed:9006946}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JV0 (NMR - ) 2QPW (X-ray 1.79A ) |
| DBSNP | rs2076324 rs17350795 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:14633678, ECO:0000269|PubMed:7538672, ECO:0000269|PubMed:9006946}. |
| Mouse PG classification | NA |
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