| Gene Information | |
|---|---|
| Gene Name | RIPK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 832 |
| Protein Names | Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase) |
| Target Name | receptor-interacting serine/threonine-protein kinase 4 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000183421 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P57078 |
| Gene Card | RIPK4 |
| Uniprot ID | P57078 |
| Pfam | PF12796; PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.021139024) |
| Ortholog in Animals | Alpaca_ RIPK4 ( ortholog_one2one ) Dog_ RIPK4 ( ortholog_one2one ) GuineaPig_ RIPK4 ( ortholog_one2one ) Macaque_ RIPK4 ( ortholog_one2one ) Mouse_ Ripk4 ( ortholog_one2one ) Pig_ RIPK4 ( ortholog_one2one ) Rat_ Ripk4 ( ortholog_one2one ) |
| Ohnologs | ANKK1 |
| Paralogs | ANKK1 |
| Tissue | brain, kidney, pancreas, small.intestine |
| Tissue Specificity | Expressed in hair follicles and skin. {ECO:0000269|PubMed:26129644}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6586239 rs387906922 rs387906923 rs764278537 rs12482626 rs55809511 rs55645753 rs55829311 rs763794698 rs56056485 rs35537517 |
| Subcellular location [CC] | Cytoplasm. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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