| Gene Information | |
|---|---|
| Gene Name | NT5C |
| Organism | Homo sapiens (Human) |
| Gene Length | 201 |
| Protein Names | 5'(3')-deoxyribonucleotidase, cytosolic type (EC 3.1.3.-) (Cytosolic 5',3'-pyrimidine nucleotidase) (Deoxy-5'-nucleotidase 1) (dNT-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000125458 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TCD5 |
| Gene Card | NT5C |
| Uniprot ID | Q8TCD5 |
| Pfam | PF06941 |
| In ASD | no |
| Allosteric Prediction | no (-0.131318502) |
| Ortholog in Animals | Alpaca_ NT5C ( ortholog_one2one ) Dog_ NT5C ( ortholog_one2one ) GuineaPig_ NT5C ( ortholog_one2one ) Macaque_ NT5C ( ortholog_one2one ) Mouse_ Nt5c ( ortholog_one2one ) Pig_ NT5C ( ortholog_one2one ) Rat_ Nt5c ( ortholog_one2one ) Rabbit_ NT5C ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NT5M |
| Tissue | NA |
| Tissue Specificity | Detected in skeletal muscle, heart and pancreas. {ECO:0000269|PubMed:10681516}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I7D (X-ray 1.20A ) 4L57 (X-ray 1.08A ) 4YIH (X-ray 1.82A ) 6G2N (X-ray 1.40A ) |
| DBSNP | rs11541956 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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