| Gene Information | |
|---|---|
| Gene Name | RIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 671 |
| Protein Names | Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q13546 |
| Gene Card | RIPK1 |
| Uniprot ID | Q13546 |
| Pfam | PF00531; PF07714; PF12721 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.265492(Rat);0.074291(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ITH (X-ray 2.25A ) 4ITI (X-ray 2.86A ) 4ITJ (X-ray 1.80A ) 4NEU (X-ray 2.57A ) 5HX6 (X-ray 2.23A ) 5TX5 (X-ray 2.56A ) 5V7Z (NMR - ) 6AC5 (X-ray 1.45A ) 6C3E (X-ray 2.60A ) 6C4D (X-ray 2.52A ) 6HHO (X-ray 3.49A ) 6NW2 (X-ray 2.00A ) 6NYH (X-ray 2.10A ) 6OCQ (X-ray 2.79A ) 6R5F (X-ray 3.25A ) 6RLN (X-ray 2.87A ) 7CJB (X-ray 2.80A ) 7FCZ (X-ray 2.21A ) 7FD0 (X-ray 2.00A ) |
| DBSNP | rs774996232 rs758268804 rs759012409 rs17548383 rs1760720617 rs34872409 rs3173519 rs35722193 rs55861377 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q60855}. Cell membrane {ECO:0000250|UniProtKB:Q9ZUF4}. |
| Mouse PG classification | NA |
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