| Gene Information | |
|---|---|
| Gene Name | RIOK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 552 |
| Protein Names | Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2) |
| Target Name | serine/threonine-protein kinase rio2 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000058729 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q9BVS4 |
| Gene Card | RIOK2 |
| Uniprot ID | Q9BVS4 |
| Pfam | PF09202 |
| In ASD | no |
| Allosteric Prediction | no (-0.977439078) |
| Ortholog in Animals | Alpaca_ RIOK2 ( ortholog_one2one ) Dog_ RIOK2 ( ortholog_one2many ) GuineaPig_ RIOK2 ( ortholog_one2one ) Macaque_ RIOK2 ( ortholog_one2one ) Mouse_ Riok2 ( ortholog_one2one ) Rat_ Riok2 ( ortholog_one2one ) Rabbit_ RIOK2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RIOK1, ATMIN, RIOK3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.355064(Mouse);0.134938(Rat);0.103012(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5DHF (X-ray 2.29A ) 6FDM (X-ray 2.10A ) 6FDN (X-ray 2.90A ) 6FDO (X-ray 2.60A ) 6G18 (EM 3.60A ) 6G51 (EM 4.10A ) 6HK6 (X-ray 2.35A ) 7VBT (X-ray 2.54A ) |
| DBSNP | rs2544773 rs35165987 rs17849382 rs34916955 rs35713904 rs147608663 rs33996030 rs160632 rs12188395 rs35829000 rs34555783 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:16037817, ECO:0000269|PubMed:19564402}. Note=Exported out of the nucleus via its NES in a XPO1-dependent manner. {ECO:0000269|PubMed:19564402}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |