| Gene Information | |
|---|---|
| Gene Name | ACOT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 421 |
| Protein Names | Peroxisomal succinyl-coenzyme A thioesterase (EC 3.1.2.3) (Acyl-coenzyme A thioesterase 4) (Acyl-CoA thioesterase 4) (EC 3.1.2.2) (PTE-2b) (Peroxisomal acyl coenzyme A thioester hydrolase Ib) (Peroxisomal long-chain acyl-CoA thioesterase Ib) (PTE-Ib) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000177465 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N9L9 |
| Gene Card | ACOT4 |
| Uniprot ID | Q8N9L9 |
| Pfam | PF08840; PF04775 |
| In ASD | no |
| Allosteric Prediction | no (-0.138296974) |
| Ortholog in Animals | Alpaca_ ACOT4 ( ortholog_one2one ) GuineaPig_ ACOT4 ( ortholog_one2one ) Mouse_ Acot4 ( ortholog_one2one ) Rat_ Acot4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACOT6, ACOT1, ACOT2, BAAT |
| Tissue | NA |
| Tissue Specificity | Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle. {ECO:0000269|PubMed:16940157}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3K2I (X-ray 2.40A ) |
| DBSNP | rs3742819 rs35724886 |
| Subcellular location [CC] | Peroxisome {ECO:0000269|PubMed:16940157}. |
| Mouse PG classification | NA |
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