| Gene Information | |
|---|---|
| Gene Name | RIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 783 |
| Protein Names | Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000174791 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q13671 |
| Gene Card | RIN1 |
| Uniprot ID | Q13671 |
| Pfam | PF00788; PF02204 |
| In ASD | no |
| Allosteric Prediction | no (-0.01898012) |
| Ortholog in Animals | Alpaca_ RIN1 ( ortholog_one2one ) Dog_ RIN1 ( ortholog_one2one ) GuineaPig_ RIN1 ( ortholog_one2one ) Macaque_ RIN1 ( ortholog_one2one ) Mouse_ Rin1 ( ortholog_one2one ) Rat_ Rin1 ( ortholog_one2one ) |
| Ohnologs | RIN3, RIN2 |
| Paralogs | RINL, RIN2, RIN3, VPS9D1, RABGEF1, GAPVD1 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined with high levels in brain, placenta and pancreas. {ECO:0000269|PubMed:9144171}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11784866}. Membrane {ECO:0000269|PubMed:11784866}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11784866}. Note=Some amount is membrane-associated. |
| Mouse PG classification | NA |
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