| Gene Information | |
|---|---|
| Gene Name | RILP |
| Organism | Homo sapiens (Human) |
| Gene Length | 831 |
| Protein Names | Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000167705 ) 3 ( ENSG00000274145 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q96MT3 |
| Gene Card | PRICKLE1 |
| Uniprot ID | Q96MT3 |
| Pfam | PF00412; PF06297 |
| In ASD | no |
| Allosteric Prediction | no (-0.433501016) |
| Ortholog in Animals | Alpaca_ RILP ( ortholog_one2one ) Dog_ RILP ( ortholog_one2one ) GuineaPig_ RILP ( ortholog_one2one ) Mouse_ Rilp ( ortholog_one2one ) Pig_ RILP ( ortholog_one2one ) Rat_ Rilp ( ortholog_one2one ) Rabbit_ RILP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RILPL1, DZIP1L, DZIP1, RILPL2 |
| Tissue | NA |
| Tissue Specificity | Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia). {ECO:0000269|PubMed:12525887, ECO:0000269|PubMed:14645515, ECO:0000269|PubMed:18976727}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs141795695 rs796052934 rs113994140 rs371720624 rs79087668 rs281865563 rs559947948 rs281865564 rs768954477 rs138452760 rs3827522 rs146670726 |
| Subcellular location [CC] | Nucleus membrane {ECO:0000269|PubMed:14645515}. Cytoplasm, cytosol {ECO:0000269|PubMed:14645515}. Note=A smaller amount is detected in the cytosol. |
| Mouse PG classification | NA |
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