Gene Information
Gene NameRIDA
OrganismHomo sapiens (Human)
Gene Length137
Protein Names2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog)
Target NameNA
Target TypeNA
Gene Age332 ( ENSG00000132541 )
Evolutionary StageCellular_organisms
AlphaFoldDBP52758
Gene CardRIDA
Uniprot IDP52758
PfamPF01042
In ASDno
Allosteric Predictionno (-0.219450892)
Ortholog in AnimalsAlpaca_ RIDA ( ortholog_one2one )
Dog_ RIDA ( ortholog_one2one )
GuineaPig_ RIDA ( ortholog_one2one )
Mouse_ Rida ( ortholog_one2one )
Pig_ RIDA ( ortholog_one2one )
Rat_ Rida ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed predominantly in liver and kidney. Lower levels in lung and brain. {ECO:0000269|PubMed:8973653, ECO:0000269|PubMed:9141440}.
Pharmacological Animal Models0.012880(Chimpanzee);0.001000(Mouse);0.001516(Rat);0.010526(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1ONI  (X-ray  1.90A 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:8973653}. Nucleus {ECO:0000269|PubMed:8973653}. Peroxisome {ECO:0000250|UniProtKB:P52759}. Mitochondrion {ECO:0000250|UniProtKB:P52759}. Note=Mostly cytoplasmic but, in less differentiated cells occasionally nuclear. {ECO:0000269|PubMed:8973653}.
Mouse PG classificationNA
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