| Gene Information | |
|---|---|
| Gene Name | RHOJ |
| Organism | Homo sapiens (Human) |
| Gene Length | 214 |
| Protein Names | Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126785 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H4E5 |
| Gene Card | RHOJ |
| Uniprot ID | Q9H4E5 |
| Pfam | PF00071 |
| In ASD | yes |
| Allosteric Prediction | no (-0.144410605) |
| Ortholog in Animals | Alpaca_ RHOJ ( ortholog_one2one ) Dog_ RHOJ ( ortholog_one2one ) GuineaPig_ RHOJ ( ortholog_one2one ) Macaque_ RHOJ ( ortholog_one2one ) Mouse_ Rhoj ( ortholog_one2one ) Pig_ RHOJ ( ortholog_one2one ) Rat_ Rhoj ( ortholog_one2one ) Rabbit_ RHOJ ( ortholog_one2one ) |
| Ohnologs | RHOQ |
| Paralogs | RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOA, RHOC, RHOB, RHOV, RHOQ, RHOBTB2, RND2, RND3, RHOD, RHOF, RHOG, RHOU, RAC2, RHOBTB1, RHOH |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver. {ECO:0000269|PubMed:21628409}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.029817(Mouse);0.003490(Rat);0.044444(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:27660391, ECO:0000269|PubMed:30158707}; Lipid-anchor {ECO:0000269|PubMed:30158707}; Cytoplasmic side {ECO:0000305}. Note=Localization to the plasma membrane is regulated by GLUL. {ECO:0000269|PubMed:30158707}. |
| Mouse PG classification | NA |
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