| Gene Information | |
|---|---|
| Gene Name | RHOBTB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 696 |
| Protein Names | Rho-related BTB domain-containing protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000072422 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O94844 |
| Gene Card | RHOBTB1 |
| Uniprot ID | O94844 |
| Pfam | PF00651; PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.026217512) |
| Ortholog in Animals | Alpaca_ RHOBTB1 ( ortholog_one2one ) Dog_ RHOBTB1 ( ortholog_one2one ) GuineaPig_ RHOBTB1 ( ortholog_one2one ) Macaque_ RHOBTB1 ( ortholog_one2one ) Mouse_ Rhobtb1 ( ortholog_one2one ) Pig_ RHOBTB1 ( ortholog_one2one ) Rat_ Rhobtb1 ( ortholog_one2one ) Rabbit_ RHOBTB1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RND1, CDC42, RHOT1, RHOBTB3, RHOT2, RAC1, RAC3, RHOJ, RHOA, RHOC, RHOB, RHOV, RHOQ, RHOBTB2, RND2, RND3, RHOD, RHOF, RHOG, RHOU, RAC2, RHOH |
| Tissue | NA |
| Tissue Specificity | Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues. {ECO:0000269|PubMed:12426103}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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