| Gene Information | |
|---|---|
| Gene Name | RHEB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | GTP-binding protein Rheb (Ras homolog enriched in brain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15382 |
| Gene Card | RHEB |
| Uniprot ID | Q15382 |
| Pfam | PF00071 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest levels observed in skeletal and cardiac muscle. {ECO:0000269|PubMed:8543055}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1XTQ (X-ray 2.00A ) 1XTR (X-ray 2.65A ) 1XTS (X-ray 2.80A ) 3SEA (X-ray 2.00A ) 3T5G (X-ray 1.70A ) 5YXH (X-ray 2.04A ) 6BCU (EM 3.43A ) 6BSX (X-ray 1.65A ) 6BT0 (X-ray 2.60A ) 7BTA (X-ray 2.60A ) 7BTC (X-ray 2.10A ) 7BTD (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endomembrane system {ECO:0000269|PubMed:22002721, ECO:0000305}; Lipid-anchor {ECO:0000269|PubMed:22002721, ECO:0000305}; Cytoplasmic side {ECO:0000269|PubMed:15489334, ECO:0000305}. Golgi apparatus membrane {ECO:0000269|PubMed:22002721}; Lipid-anchor {ECO:0000305|PubMed:22002721}; Cytoplasmic side {ECO:0000305|PubMed:22002721}. Cytoplasm, cytosol {ECO:0000269|PubMed:22002721}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22002721}; Lipid-anchor {ECO:0000269|PubMed:22002721}; Cytoplasmic side {ECO:0000269|PubMed:22002721}. |
| Mouse PG classification | NA |
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