Gene Information
Gene NameRHCG
OrganismHomo sapiens (Human)
Gene Length479
Protein NamesAmmonium transporter Rh type C (Rh glycoprotein kidney) (Rhesus blood group family type C glycoprotein) (Rh family type C glycoprotein) (Rh type C glycoprotein) (Tumor-related protein DRC2)
Target Nameammonium transporter rh type c
Target TypeLiterature-reported target
Gene Age1064 ( ENSG00000140519 )
Evolutionary StageEukaryota
AlphaFoldDBQ9UBD6
Gene CardRHCG
Uniprot IDQ9UBD6
PfamPF00909
In ASDno
Allosteric Predictionno (-0.775749483)
Ortholog in AnimalsAlpaca_ RHCG ( ortholog_one2one )
Dog_ RHCG ( ortholog_one2one )
GuineaPig_ RHCG ( ortholog_one2one )
Macaque_ RHCG ( ortholog_one2one )
Mouse_ Rhcg ( ortholog_one2one )
Pig_ RHCG ( ortholog_one2one )
Rat_ Rhcg ( ortholog_one2one )
Rabbit_ RHCG ( ortholog_one2one )
OhnologsRHAG, RHBG
ParalogsRHBG, RHAG, RHCE, RHD
Tissueesophagus, cervix, tongue, kidney, esophagus.mucosa
Tissue SpecificityExpressed in brain, testis, placenta, pancreas, esophagus and prostate. Expressed in squamous epithelial tissues (at protein level). According to PubMed:11062476, specifically expressed in kidney. {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:11062476, ECO:0000269|PubMed:12204676}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3HD6  (X-ray  2.10A 
DBSNP rs17807723 
Subcellular location [CC]Apical cell membrane {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:12204676};
Multi-pass membrane protein {ECO:0000269|PubMed:10852913, ECO:0000269|PubMed:12204676}. Note=Also detected at the basolateral membrane and in subapical vesicles. {ECO:0000250}.
Mouse PG classificationNA
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