Gene Information
Gene NameRGS5
OrganismHomo sapiens (Human)
Gene Length181
Protein NamesRegulator of G-protein signaling 5 (RGS5)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000143248 )
Evolutionary StageEukaryota
AlphaFoldDBO15539
Gene CardRGS5
Uniprot IDO15539
PfamPF00615
In ASDno
Allosteric Predictionno (-1.144764596)
Ortholog in AnimalsAlpaca_ RGS5 ( ortholog_one2one )
Dog_ RGS5 ( ortholog_one2one )
GuineaPig_ RGS5 ( ortholog_one2one )
Macaque_ RGS5 ( ortholog_one2one )
Mouse_ Rgs5 ( ortholog_one2one )
Pig_ RGS5 ( ortholog_one2one )
Rat_ Rgs5 ( ortholog_one2one )
Rabbit_ RGS5 ( ortholog_one2one )
OhnologsNA
ParalogsRGS18, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2CRP  (NMR 
DBSNP NA 
Subcellular location [CC][Isoform 1]: Cytoplasm {ECO:0000269|PubMed:15670159}. Membrane {ECO:0000269|PubMed:15670159}.;
[Isoform 2]: Cytoplasm {ECO:0000269|PubMed:15670159}.
Mouse PG classificationHPG
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