| Gene Information | |
|---|---|
| Gene Name | RGS4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | Regulator of G-protein signaling 4 (RGP4) (RGS4) |
| Target Name | regulator of g-protein signaling 4 |
| Target Type | Literature-reported target |
| Gene Age | 886 ( ENSG00000117152 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49798 |
| Gene Card | RGS4 |
| Uniprot ID | P49798 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | yes (0.144546116) |
| Ortholog in Animals | Alpaca_ RGS4 ( ortholog_one2one ) Dog_ RGS4 ( ortholog_one2one ) GuineaPig_ RGS4 ( ortholog_one2one ) Macaque_ RGS4 ( ortholog_one2one ) Mouse_ Rgs4 ( ortholog_one2one ) Pig_ RGS4 ( ortholog_one2one ) Rat_ Rgs4 ( ortholog_one2one ) Rabbit_ RGS4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RGS18, RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | cerebral.cortex, adrenal.gland, brain |
| Tissue Specificity | Expressed in brain and heart. Expressed in brain at protein level. Expressed in prefontal and visual cortex. Isoform 4 and isoform 5 are expressed ubiquitously. Isoform 1, isoform 2 and isoform 3 are not expressed in the cerebellum. {ECO:0000269|PubMed:17707117}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs14665 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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