| Gene Information | |
|---|---|
| Gene Name | RGS22 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1264 |
| Protein Names | Regulator of G-protein signaling 22 (RGS22) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000132554 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NE09 |
| Gene Card | RGS22 |
| Uniprot ID | Q8NE09 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-1.325393209) |
| Ortholog in Animals | Alpaca_ RGS22 ( ortholog_one2one ) Dog_ RGS22 ( ortholog_one2one ) GuineaPig_ RGS22 ( ortholog_one2one ) Macaque_ RGS22 ( ortholog_one2one ) Mouse_ Rgs22 ( ortholog_one2one ) Pig_ RGS22 ( ortholog_one2one ) Rat_ Rgs22 ( ortholog_one2one ) Rabbit_ RGS22 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RGS18, RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | testis |
| Tissue Specificity | Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level). {ECO:0000269|PubMed:18703424}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2446927 rs3133711 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18703424}. Nucleus {ECO:0000269|PubMed:18703424}. Note=Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus. |
| Mouse PG classification | NA |
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