| Gene Information | |
|---|---|
| Gene Name | RGS18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 235 |
| Protein Names | Regulator of G-protein signaling 18 (RGS18) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000150681 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NS28 |
| Gene Card | RGS18 |
| Uniprot ID | Q9NS28 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | yes (0.224532128) |
| Ortholog in Animals | Alpaca_ RGS18 ( ortholog_one2one ) Dog_ RGS18 ( ortholog_one2one ) GuineaPig_ RGS18 ( ortholog_one2one ) Macaque_ RGS18 ( ortholog_one2one ) Mouse_ Rgs18 ( ortholog_one2one ) Pig_ RGS18 ( ortholog_one2one ) Rat_ Rgs18 ( ortholog_one2one ) Rabbit_ RGS18 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | adipose.tissue, lung, ovary, sigmoid.colon, spleen, whole.blood |
| Tissue Specificity | Expressed in peripheral leukocytes, bone marrow, platelet, spleen and fetal liver. {ECO:0000269|PubMed:11042171, ECO:0000269|PubMed:11955952}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2DLV (NMR - ) 2JM5 (NMR - ) 2OWI (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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