| Gene Information | |
|---|---|
| Gene Name | RGS16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 202 |
| Protein Names | Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000143333 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O15492 |
| Gene Card | RGS16 |
| Uniprot ID | O15492 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-0.158113064) |
| Ortholog in Animals | Alpaca_ RGS16 ( ortholog_one2one ) Dog_ RGS16 ( ortholog_one2one ) GuineaPig_ RGS16 ( ortholog_one2one ) Macaque_ RGS16 ( ortholog_one2one ) Mouse_ Rgs16 ( ortholog_one2one ) Pig_ RGS16 ( ortholog_one2one ) Rat_ Rgs16 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RGS8, RGS18, RGS5, RGS3, RGS20, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS10 |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in retina with lower levels of expression in most other tissues. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BT2 (X-ray 1.90A ) 2IK8 (X-ray 2.71A ) |
| DBSNP | rs1144566 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:P97428}; Lipid-anchor {ECO:0000250|UniProtKB:P97428}. |
| Mouse PG classification | NA |
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