| Gene Information | |
|---|---|
| Gene Name | TERF2IP |
| Organism | Homo sapiens (Human) |
| Gene Length | 399 |
| Protein Names | Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Dopamine receptor-interacting protein 5) (Repressor/activator protein 1 homolog) (RAP1 homolog) (hRap1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000166848 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9NYB0 |
| Gene Card | TERF2IP |
| Uniprot ID | Q9NYB0 |
| Pfam | PF16589; PF08914; PF11626 |
| In ASD | no |
| Allosteric Prediction | no (-0.018846297) |
| Ortholog in Animals | Alpaca_ TERF2IP ( ortholog_one2one ) Dog_ TERF2IP ( ortholog_one2one ) GuineaPig_ TERF2IP ( ortholog_one2one ) Macaque_ TERF2IP ( ortholog_one2one ) Mouse_ Terf2ip ( ortholog_one2one ) Pig_ TERF2IP ( ortholog_one2one ) Rat_ Terf2ip ( ortholog_one2one ) Rabbit_ TERF2IP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.06(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1FEX (NMR - ) 3K6G (X-ray 1.95A ) 4RQI (X-ray 2.44A ) |
| DBSNP | rs4888444 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q91VL8}. Cytoplasm {ECO:0000250|UniProtKB:Q91VL8}. Chromosome {ECO:0000250|UniProtKB:Q91VL8}. Chromosome, telomere {ECO:0000250|UniProtKB:Q91VL8}. Note=Associates with chromosomes, both at telomeres and in extratelomeric sites. Also exists as a cytoplasmic form, where it associates with the IKK complex. {ECO:0000250|UniProtKB:Q91VL8}. |
| Mouse PG classification | NA |
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