| Gene Information | |
|---|---|
| Gene Name | RGR |
| Organism | Homo sapiens (Human) |
| Gene Length | 291 |
| Protein Names | RPE-retinal G protein-coupled receptor |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000148604 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P47804 |
| Gene Card | RGR |
| Uniprot ID | P47804 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.24788693) |
| Ortholog in Animals | Alpaca_ RGR ( ortholog_one2one ) Dog_ RGR ( ortholog_one2one ) GuineaPig_ RGR ( ortholog_one2one ) Macaque_ RGR ( ortholog_one2one ) Mouse_ Rgr ( ortholog_one2one ) Pig_ RGR ( ortholog_one2one ) Rat_ Rgr ( ortholog_one2one ) Rabbit_ RGR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CCR9, CXCR6, CCR7, CCR6, ACKR4, CCR10, CXCR5, CXCR4, CXCR1, CXCR2, CXCR3, CCRL2, CCR8, CCR1, ACKR2, CCR4, CX3CR1, CCR2, CCR5, CCR3, GALR2, ACKR3, XCR1 |
| Tissue | brain |
| Tissue Specificity | Preferentially expressed at high levels in the retinal pigment epithelium (RPE) and Mueller cells of the neural retina. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs104894187 rs370808520 rs150808273 rs377043137 rs61730895 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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