| Gene Information | |
|---|---|
| Gene Name | RGMA |
| Organism | Homo sapiens (Human) |
| Gene Length | 450 |
| Protein Names | Repulsive guidance molecule A (RGM domain family member A) |
| Target Name | repulsive guidance molecule a |
| Target Type | Clinical trial target |
| Gene Age | 950 ( ENSG00000182175 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96B86 |
| Gene Card | RGMA |
| Uniprot ID | Q96B86 |
| Pfam | PF06534; PF06535 |
| In ASD | no |
| Allosteric Prediction | no (-1.007735514) |
| Ortholog in Animals | Alpaca_ RGMA ( ortholog_one2one ) Dog_ RGMA ( ortholog_one2one ) GuineaPig_ RGMA ( ortholog_one2one ) Macaque_ RGMA ( ortholog_one2one ) Mouse_ Rgma ( ortholog_one2one ) Pig_ RGMA ( ortholog_one2one ) Rat_ Rgma ( ortholog_one2one ) Rabbit_ RGMA ( ortholog_one2one ) |
| Ohnologs | HJV, RGMB |
| Paralogs | HJV, RGMB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4UHY (X-ray 3.20A ) 6Z3G (X-ray 2.78A ) |
| DBSNP | rs4238485 rs4778078 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
| Mouse PG classification | NA |
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