| Gene Information | |
|---|---|
| Gene Name | G6PC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 355 |
| Protein Names | Glucose-6-phosphatase 2 (G-6-Pase 2) (G6Pase 2) (EC 3.1.3.9) (Islet-specific glucose-6-phosphatase catalytic subunit-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000152254 ) 3 ( ENSG00000278373 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NQR9 |
| Gene Card | G6PC2 |
| Uniprot ID | Q9NQR9 |
| Pfam | PF01569 |
| In ASD | no |
| Allosteric Prediction | yes (0.295601487) |
| Ortholog in Animals | Alpaca_ G6PC2 ( ortholog_one2one ) Dog_ G6PC2 ( ortholog_one2one ) GuineaPig_ G6PC2 ( ortholog_one2one ) Macaque_ G6PC2 ( ortholog_one2one ) Mouse_ G6pc2 ( ortholog_one2one ) Pig_ G6PC2 ( ortholog_one2one ) Rat_ AABR07052465.1 ( ortholog_one2one ) Rabbit_ G6PC2 ( ortholog_one2one ) |
| Ohnologs | G6PC1, G6PC3 |
| Paralogs | G6PC1, G6PC3 |
| Tissue | pancreas |
| Tissue Specificity | Specifically expressed in pancreas and also detected to a lower extent in testis. Expressed by most islet cells in the pancreas (at protein level). {ECO:0000269|PubMed:11297555}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2232322 rs2232323 rs492594 rs2232326 rs2232327 rs2232328 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15044018}; Multi-pass membrane protein {ECO:0000269|PubMed:15044018}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |