| Gene Information | |
|---|---|
| Gene Name | RGCC |
| Organism | Homo sapiens (Human) |
| Gene Length | 137 |
| Protein Names | Regulator of cell cycle RGCC (Response gene to complement 32 protein) (RGC-32) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000102760 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H4X1 |
| Gene Card | RGCC |
| Uniprot ID | Q9H4X1 |
| Pfam | PF15151 |
| In ASD | no |
| Allosteric Prediction | no (-0.297501559) |
| Ortholog in Animals | Alpaca_ RGCC ( ortholog_one2one ) Dog_ RGCC ( ortholog_one2one ) GuineaPig_ RGCC ( ortholog_one2one ) Macaque_ RGCC ( ortholog_one2one ) Mouse_ Rgcc ( ortholog_one2one ) Pig_ RGCC ( ortholog_one2one ) Rat_ Rgcc ( ortholog_one2many ) Rat_ AABR07048653.1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in brain, heart and liver (at protein level). Highly expressed in liver, skeletal muscle, kidney and pancreas. Detected at lower levels in heart, brain and placenta. Detected in aorta endothelial cells. Overexpressed in colon, breast, prostate, bladder, lung, and ovarian cancer tissues. {ECO:0000269|PubMed:11687586, ECO:0000269|PubMed:15713436}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic in unstimulated cells. Nuclear after activation by complement. Associated with the centrosome during prometaphase and metaphase. |
| Mouse PG classification | NA |
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