Gene Information | |
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Gene Name | RG4 |
Organism | Homo sapiens (Human) |
Gene Length | 240 |
Protein Names | Protein unc-119 homolog A (Retinal protein 4) (hRG4) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | Q13432 |
Gene Card | UNC119 |
Uniprot ID | Q13432 |
Pfam | PF05351 |
In ASD | no |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Abundantly expressed in retina, in photoreceptor synapses and inner segments. Expressed in a much lesser extent in several other tissues. {ECO:0000269|PubMed:9761287}. |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.011765(Rabbit) |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 3GQQ (X-ray 1.95A ) 3RBQ (X-ray 2.00A ) 4GOJ (X-ray 2.10A ) 4GOK (X-ray 2.60A ) 5L7K (X-ray 2.10A ) 6H6A (X-ray 2.00A ) |
DBSNP | rs199714731 |
Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23535298}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:23535298}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23535298}. Note=Localizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells. {ECO:0000269|PubMed:23535298}. |
Mouse PG classification | NA |
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