Gene Information
Gene NameRG4
OrganismHomo sapiens (Human)
Gene Length240
Protein NamesProtein unc-119 homolog A (Retinal protein 4) (hRG4)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ13432
Gene CardUNC119
Uniprot IDQ13432
PfamPF05351
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityAbundantly expressed in retina, in photoreceptor synapses and inner segments. Expressed in a much lesser extent in several other tissues. {ECO:0000269|PubMed:9761287}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.011765(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3GQQ  (X-ray  1.95A  3RBQ  (X-ray  2.00A  4GOJ  (X-ray  2.10A  4GOK  (X-ray  2.60A  5L7K  (X-ray  2.10A  6H6A  (X-ray  2.00A 
DBSNP rs199714731 
Subcellular location [CC]Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23535298}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:23535298}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23535298}. Note=Localizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis;
it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells. {ECO:0000269|PubMed:23535298}.
Mouse PG classificationNA
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